Dr. Giacomazzi obtained the degree of "Docteur Es Sciences" (PhD) at the Swiss Federal Institute of Technology in Lausanne in 2007, with a thesis dedicated to the first principle modeling of the vibrational spectra of tetrahedrally-bonded glasses: SiO2, GeO2, and GeSe2.

He then moved, as a PostDoc, to Trieste where he worked for several institutions (CNR, SISSA, AREA Science Park FVG) on research projects concerning both high pressure physics, physics of amorphous materials, and point defects in glasses, further developing his expertise in ab-initio methods, in particular for the calculation of electron paramagnetic resonance (EPR) parameters. In 2018 he moved to the University of Nova Gorica (Slovenia) as assistant Professor in the Materials Research Laboratory. Next, he joined the CNR-IOM in 2022 as a staff researcher.

In the last decade, his research activity has concerned mainly the first-principle computational modeling of materials relevant for microelectronics and optical fiber technology, in the frame of a longstanding international collaboration devoted to the study of defects and irradiation effects in semiconductors and insulators.